New mRNA cancer vaccine triggers fierce immune response to fight malignant brain tumor

Published on May 1, 2024

An mRNA cancer vaccine quickly reprogrammed the immune system to attack the most aggressive type of brain tumor in a first-ever human clinical trial.

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Microarray patches safe and effective for vaccinating children, trial suggests

April 30, 2024
The first study of the use of microarray patches to vaccinate children has shown that the method is safe and induces strong immune responses. The phase 1/2 randomized trial compared results from the measles and rubella vaccine delivered by a microarray patch, a small sticking plaster-like device with an array of microscopic projections that painlessly penetrate the skin and deliver the vaccine, or

New strategy could lead to universal, long-lasting flu shot

May 1, 2024
An experimental influenza vaccine carrying more than 80,000 variations of hemagglutinin antigens caused the immune system of mice and ferrets to respond more strongly to less variable portions of the virus. This is a big step forward in efforts at the Duke Human Vaccine Institute to develop a universal, long-lasting flu shot.